Cardiovascular Medicine
Should Neutral Trials Change Practice - Lessons from HFpEF
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Duration: 30 minutes
Featuring: Drs Milan Gupta, Narendra Singh
Credits: N/A
CLICK HERE TO LISTEN

Resources:
Audio recording

This program was developed by the Canadian Collaborative Research Network.

Program Description:

Heart failure with preserved EF (HFpEF) carries substantial morbidity and mortality, yet evidence-based treatments to improve outcomes are sorely lacking. Recently, the FDA made the unusual decision to approve sacubitril/valsartan for HFpEF despite a neutral trial with this agent. Similarly, while spironolactone’s major trial in HFpEF was not positive, guidelines have endorsed this therapy based on sub-group analyses. This podcast will explore why these decisions were made and whether these treatments should be considered for HFpEF patients.

Learning Objectives:

  • To review current treatment strategies for HFpEF
  • To understand how neutral trials may still influence guidelines and practice

 

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Image
Duration: 30 minutes
Featuring: Drs Milan Gupta, Narendra Singh
Credits: N/A
CLICK HERE TO LISTEN

Resources:
Audio recording

This program was developed by the Canadian Collaborative Research Network.

Program Description:

Heart failure with preserved EF (HFpEF) carries substantial morbidity and mortality, yet evidence-based treatments to improve outcomes are sorely lacking. Recently, the FDA made the unusual decision to approve sacubitril/valsartan for HFpEF despite a neutral trial with this agent. Similarly, while spironolactone’s major trial in HFpEF was not positive, guidelines have endorsed this therapy based on sub-group analyses. This podcast will explore why these decisions were made and whether these treatments should be considered for HFpEF patients.

Learning Objectives:

  • To review current treatment strategies for HFpEF
  • To understand how neutral trials may still influence guidelines and practice

 

This program is NOT accredited.

Mainpro+ participants may earn certified credits by completing a Linking Learning Exercise.

Specialist participants may claim Section 2 credits (up to 2 credits per hour) following completion of a personal learning project (PLP) under Section 2: Self-Learning Activities within the MAINPORT ePortfolio. 

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Narendra Singh
MD, FRCPC, FCCS, FACC, FAHA

MD, FRCPC, FCCS, FACC, FAHA

Director, NSC Cardiology
Clinical Assistant Professor,
Medical College of Georgia at
Augusta University and Mercer University
Atlanta, GA

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Milan Gupta

MD, FRCPC, FCCS, CPC(HC)

Assistant Professor, Department of Medicine, University of Toronto

Medical Director, Canadian Collaborative Research Network

Brampton, ON 

This program was developed by the Canadian Collaborative Research Network, a not-for-profit physician organization.  No outside funding support was received for this program. 

Continue learning with MDRead

Published on March 31, 2022

I’m ready to use natriuretic peptide testing in my patients with dyspnea to diagnose heart failure...

How to incorporate BNP testing into primary care....

Published on May 06, 2022

Hypertension- A Salty Topic

Why are we still talking about hypertension?   &nbs...

Published on October 13, 2022

SOME CALL IT SLEEP

What’s New in Insomnia Management and Treatment &ld...